2,6-dimethoxypyridin-3-amine monohydrochloride - Names and Identifiers
2,6-dimethoxypyridin-3-amine monohydrochloride - Physico-chemical Properties
Molecular Formula | C7H11ClN2O2
|
Molar Mass | 190.63 |
Melting Point | 212°C(lit.) |
Boling Point | 265.7°C at 760 mmHg |
Flash Point | 114.5°C |
Vapor Presure | 0.00902mmHg at 25°C |
Storage Condition | Room Temprature |
2,6-dimethoxypyridin-3-amine monohydrochloride - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
WGK Germany | 3 |
HS Code | 29333999 |
2,6-dimethoxypyridin-3-amine monohydrochloride - Introduction
3-Amino-2,6-dimethoxypyridine monohydrochloride is an organic compound with the chemical formula C7H10ClNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in water and alcohol solvents, slightly soluble in ether solvents
-Melting point: about 170 ℃
- pH: about 4-5
Use:
-Pharmaceutical field: 3-Amino-2,6-dimethoxypyridine monohydrochloride is commonly used as an intermediate and synthetic raw material for the preparation of drugs, pesticides and dyes.
-Scientific research: It can also be used as reaction catalysts and reagents in organic chemical synthesis.
Preparation Method:
3-Amino-2,6-dimethoxypyridine monohydrochloride can be synthesized by the following steps:
1. Pyridine reacts with silver nitrite to produce 2-nitropyridine.
2. 2-Nitropyridine was converted to 2-aminopyridine by reduction reaction.
3. 2-Aminopyridine reacts with methanol to obtain 3-amino -2, 6-dimethoxypyridine by alkylation.
4. 3-Amino-2,6-dimethoxypyridine reacts with hydrochloric acid to generate 3-Amino-2,6-dimethoxypyridine monohydrochloride.
Safety Information:
- 3-Amino-2,6-dimethoxypyridine monohydrochloride is an organic compound and has certain toxicity. Please pay attention to safe operation and comply with laboratory safety regulations.
-Use protective gloves and glasses to avoid contact with skin and eyes.
-Avoid inhaling dust or gas and maintain a well-ventilated laboratory operating environment.
-During storage, it is recommended to keep dry and sealed to avoid contact with oxidizing agents.
Last Update:2024-04-09 15:18:00